Part I: Background Cases across the nation Brown v. Board of Education of Topeka (1954) is widely cited, and rightly so, as the case that started it… Read more “Boston School Desegregation”
Author: Zane Griffin
Anxiolytic Effects of CBD (critique paper)
Introduction In search of finding the neurobiological underpinnings by which cannabidiol (CBD) could possibly exert an anxiolytic effect on the brain, Jose Crippa et. al. designed what… Read more “Anxiolytic Effects of CBD (critique paper)”
CBD as a novel treatment for context induced relapse to cocaine: Neurobiological attenuation of the cocaine-glutamate response via Ca2+ increase (Research Proposal)
Specific Aim / Research Questions: A growing body of work since the beginning of the 21st century has targeted the endocannabinoid system and its role in learned… Read more “CBD as a novel treatment for context induced relapse to cocaine: Neurobiological attenuation of the cocaine-glutamate response via Ca2+ increase (Research Proposal)”
Teens and Addiction: Risk Taking and Impulsivity in Addiction Vulnerability
Biological imperative demands that all animals venture from the nest in order to propagate and reproduce. In the wild this means encountering dangerous situations where survival will… Read more “Teens and Addiction: Risk Taking and Impulsivity in Addiction Vulnerability”
Corticostriatal-limbic Pathways: The Impact of Stress during Development in Addiction Vulnerability
A signature feature of post traumatic stress disorder (PTSD) is hyperreactivity and overgeneralization to potentially threatening or stressful stimuli. This hyperarousal shares similar physiological and behavioral maladaptations… Read more “Corticostriatal-limbic Pathways: The Impact of Stress during Development in Addiction Vulnerability”
CB1 Receptor Antagonists in Addiction Treatment
Among some of the more promising developments in addiction treatment involve the use of cannabinoid receptor (CB1) antagonists. Namely SR141716A, also known as Rimonabant, and AM251 have… Read more “CB1 Receptor Antagonists in Addiction Treatment”
Alterations in Endocannabinoid Signalling Pathways of the VTA from Prenatal Ethanol Exposure
Embryonic development and early gestation are critical times in which the developing fetus is highly susceptible to external toxins and environmental factors. The first sixty days of… Read more “Alterations in Endocannabinoid Signalling Pathways of the VTA from Prenatal Ethanol Exposure”
Biological Sex Differences in Addiction
In experimental studies, researchers have been able to induce conditions which mimic behavioral patterns seen in clinical human populations of drug addicts. These conditions provide support for… Read more “Biological Sex Differences in Addiction”
Obsessive Compulsive and Impulse Control Disorders as an Analog for Addiction Pathogenesis
The purpose and focus of much of the current addiction research literature is identifying and elaborating on mechanisms which underpin the ‘switch’ from impulsive drug use to… Read more “Obsessive Compulsive and Impulse Control Disorders as an Analog for Addiction Pathogenesis”
